全部产品分类
品牌 |
Leading Biology | 货号 |
AMM05870G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FKBP1B antibody (N-term).
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分子量 |
11783 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Sarcoplasmic reticulum
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
16-46 aa
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靶点 |
This FKBP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human FKBP1B.
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亚型 |
Rabbit Ig
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通用名 |
FKBP12.6, FKBP1L, FKBP9, OTK4
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基因ID |
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UniProt ID |
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功能 |
Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
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总结 |
FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
IF~~1:10~50
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别名 |
Peptidyl-prolyl cis-trans isomerase FKBP1B, PPIase FKBP1B, 126 kDa FK506-binding protein, 126 kDa FKBP, FKBP-126, FK506-binding protein 1B, FKBP-1B, Immunophilin FKBP126, Rotamase, h-FKBP-12, FKBP1B, FKBP126, FKBP1L, FKBP9, OTK4
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图像 |
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说明书 |
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数量 |
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