品牌 |
Leading Biology | 货号 |
APG01995G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Aromatase (CYP19A1) antibody (Center).
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分子量 |
57883 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Peripheral membrane protein.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
221-253 aa
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靶点 |
This Aromatase (CYP19A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-253 amino acids from the Central region of human Aromatase (CYP19A1).
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亚型 |
Rabbit Ig
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通用名 |
ARO1, CYAR, CYP19
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
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总结 |
CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19
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图像 |
Western blot analysis of anti-CYP19A1(Center) Pab (Cat. APG01995G) in HL60 cell line lysates (35ug/lane). CYP19A1(arrow) was detected using the purified Pab. |
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说明书 |
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数量 |
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