品牌 |
Leading Biology | 货号 |
APG01671G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AKR7A2 antibody (N-term).
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分子量 |
39589 Da
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细胞定位 |
Antigen Cellular Localization:
Golgi apparatus. Cytoplasm
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
101-129 aa
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靶点 |
This AKR7A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the N-terminal region of human AKR7A2.
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亚型 |
Rabbit Ig
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通用名 |
AFAR, AFAR1, AKR7
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2- nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
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总结 |
AKR7A2 is aldo-keto reductases, which are involved in the detoxification of aldehydes and ketones.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Aflatoxin B1 aldehyde reductase member 2, 111n11, AFB1 aldehyde reductase 1, AFB1-AR 1, Aldoketoreductase 7, Succinic semialdehyde reductase, SSA reductase, AKR7A2, AFAR, AFAR1, AKR7
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图像 |
Western blot analysis of anti-AKR7A2 antibody (N-term) (Cat. APG01671G) in 293 cell line lysates (35ug/lane). AKR7A2 (arrow) was detected using the purified Pab. Western blot analysis of anti-AKR7A2 Antibody (N-term) (Cat. APG01671G) in mouse liver tissue lysates (35ug/lane). AKR7A2 (arrow) was detected using the purified Pab . |
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说明书 |
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数量 |
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