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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > AKR7A2 Antibody (N-term)

AKR7A2 Antibody (N-term)

货号 货期 规格 / 价格 询价
APG01671G 100 μl / ¥4950

AKR7A2 Antibody (N-term)

品牌

Leading Biology

货号

APG01671G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AKR7A2 antibody (N-term).

分子量

39589 Da

细胞定位

Antigen Cellular Localization: Golgi apparatus. Cytoplasm

宿主

Rabbit

种属反应性

Human, Mouse

免疫原

101-129 aa

靶点

This AKR7A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the N-terminal region of human AKR7A2.

亚型

Rabbit Ig

通用名

AFAR, AFAR1, AKR7

基因ID

UniProt ID

功能

Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2- nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

总结

AKR7A2 is aldo-keto reductases, which are involved in the detoxification of aldehydes and ketones.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

别名

Aflatoxin B1 aldehyde reductase member 2, 111n11, AFB1 aldehyde reductase 1, AFB1-AR 1, Aldoketoreductase 7, Succinic semialdehyde reductase, SSA reductase, AKR7A2, AFAR, AFAR1, AKR7

图像

Western blot analysis of anti-AKR7A2 antibody (N-term) (Cat. APG01671G) in 293 cell line lysates (35ug/lane). AKR7A2 (arrow) was detected using the purified Pab. Western blot analysis of anti-AKR7A2 Antibody (N-term) (Cat. APG01671G) in mouse liver tissue lysates (35ug/lane). AKR7A2 (arrow) was detected using the purified Pab .

说明书

数量

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