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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > FUCA1 Antibody (Center)

FUCA1 Antibody (Center)

货号 货期 规格 / 价格 询价
AMM04633G 100 μl / ¥4950

FUCA1 Antibody (Center)

品牌

Leading Biology

货号

AMM04633G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FUCA1 antibody (Center).

分子量

53689 Da

细胞定位

Antigen Cellular Localization: Lysosome.

宿主

Rabbit

种属反应性

Human

免疫原

265-294 aa

靶点

This FUCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human FUCA1.

亚型

Rabbit Ig

基因ID

UniProt ID

功能

Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins.

总结

FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, FC, E

稀释方法

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

别名

Tissue alpha-L-fucosidase, Alpha-L-fucosidase I, Alpha-L-fucoside fucohydrolase 1, Alpha-L-fucosidase 1, FUCA1

图像

Western blot analysis of FUCA1 Antibody (Center) (Cat. AMM04633G) in HepG2 cell line lysates (35ug/lane). FUCA1 (arrow) was detected using the purified Pab.

FUCA1 Antibody (Center) (Cat. AMM04633G) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FUCA1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

FUCA1 Antibody (Center) (Cat. AMM04633G) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

说明书

数量

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