全部产品分类
品牌 |
Leading Biology | 货号 |
APG01897G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AOX1 antibody (Center).
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分子量 |
147918 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
698-726 aa
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靶点 |
This AOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-726 amino acids from the Central region of human AOX1.
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亚型 |
Rabbit Ig
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通用名 |
AO
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基因ID |
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UniProt ID |
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功能 |
Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N- methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.
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总结 |
AOX1 catalyzes: An aldehyde + H2O + O2 = a carboxylic acid + H2O2.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, FC, E
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稀释方法 |
WB~~1:1000
FC~~1:10~50
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别名 |
Aldehyde oxidase, Aldehyde oxidase 1, Azaheterocycle hydroxylase, 1173-, AOX1, AO
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图像 |
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说明书 |
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数量 |
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