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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > RRAGD Antibody (Center)

RRAGD Antibody (Center)

货号 货期 规格 / 价格 询价
AMM07666G 100 μl / ¥4950

RRAGD Antibody (Center)

品牌

Leading Biology

货号

AMM07666G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RRAGD antibody (Center).

分子量

45588 Da

细胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA

宿主

Rabbit

种属反应性

Human, Mouse

免疫原

171-199 aa

靶点

This RRAGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human RRAGD.

亚型

Rabbit Ig

基因ID

UniProt ID

功能

Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.

总结

RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, FC, E

稀释方法

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

别名

Ras-related GTP-binding protein D, Rag D, RagD, RRAGD (HGNC:19903)

图像

Anti-RRAGD Antibody (Center) at 1:1000 dilution + 293T/17 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 46 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of RRAGD Antibody (Center) (Cat. AMM07666G) in MDA-MB435 cell line lysates (35ug/lane). RRAGD (arrow) was detected using the purified Pab.

Western blot analysis of RRAGD Antibody (Center) (Cat. AMM07666G) in mouse cerebellum tissue lysates (35ug/lane). RRAGD (arrow) was detected using the purified Pab.

说明书

数量

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