全部产品分类
品牌 |
Leading Biology | 货号 |
AMR09801G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality S47A2 antibody (N-term).
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分子量 |
65085 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of the proximal tubules
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
125-153 aa
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靶点 |
This S47A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the N-terminal region of human S47A2.
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亚型 |
Rabbit Ig
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通用名 |
MATE2
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基因ID |
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UniProt ID |
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功能 |
Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.
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总结 |
S47A2 belongs to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Multidrug and toxin extrusion protein 2, MATE-2, hMATE-2, Kidney-specific H(+)/organic cation antiporter, Solute carrier family 47 member 2, SLC47A2, MATE2
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图像 |
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说明书 |
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数量 |
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