品牌 |
Leading Biology | 货号 |
APR09182G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-IRS2(Y978) antibody.
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分子量 |
137334 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol.
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
This IRS2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y978 of human IRS2.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May mediate the control of various cellular processes by insulin.
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总结 |
Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
DB, E
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稀释方法 |
DB~~1:500
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别名 |
Insulin receptor substrate 2, IRS-2, IRS2
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图像 |
Dot blot analysis of anti-Phospho-IRS2-pY978 Antibody (Cat. APR09182G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
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说明书 |
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数量 |
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