品牌 |
Leading Biology | 货号 |
APR09110G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PHB1 antibody (C-term).
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分子量 |
29804 Da
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion inner membrane.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
182-211 aa
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靶点 |
This PHB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from the C-terminal region of human PHB1.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
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总结 |
Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Prohibitin, PHB
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图像 |
Western blot analysis of PHB1 (arrow) using rabbit polyclonal PHB1 Antibody (Human C-term) (Cat. APR09110G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PHB1 gene (Lane 2) (Origene Technologies). |
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说明书 |
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数量 |
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