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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > ZMPSTE24 Antibody (Center)

ZMPSTE24 Antibody (Center)

货号 货期 规格 / 价格 询价
APR14303G 100 μl / ¥4950

ZMPSTE24 Antibody (Center)

品牌

Leading Biology

货号

APR14303G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZMPSTE24 antibody (Center).

分子量

54813 Da

细胞定位

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein

宿主

Rabbit

种属反应性

Human, Mouse

免疫原

400-430 aa

靶点

This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-430 amino acids from the Central region of human ZMPSTE24.

亚型

Rabbit Ig

通用名

FACE1, STE24

基因ID

UniProt ID

功能

Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.

总结

ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

WB~~1:1000 IHC-P~~1:50~100

别名

CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24

图像

All lanes : Anti-ZMPSTE24 Antibody (E415) at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: human kidney lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 55 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

The anti-ZMPSTE24 Pab (Cat. APR14303G) is used in Western blot to detect ZMPSTE24 in mouse cerebellum tissue lysate.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

说明书

数量

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