全部产品分类
品牌 |
Leading Biology | 货号 |
AMM06907G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality OPHN1 antibody (Center).
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分子量 |
91641 Da
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细胞定位 |
Antigen Cellular Localization:
Cell junction, synapse. Cell projection, axon. Cell projection, dendritic spine. Cell projection, dendrite. Cytoplasm. Note=Present in both presynaptic and postsynaptic sites.
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
This OPHN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 284-315 amino acids from the Central region of human OPHN1.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).
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总结 |
Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Oligophrenin-1, OPHN1
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图像 |
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说明书 |
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数量 |
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