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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > SDHB Antibody (C-term)

SDHB Antibody (C-term)

货号 货期 规格 / 价格 询价
APR07172G 100 μl / ¥4950

SDHB Antibody (C-term)

品牌

Leading Biology

货号

APR07172G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SDHB antibody (C-term).

分子量

31630 Da

细胞定位

Antigen Cellular Localization: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side

宿主

Rabbit

种属反应性

Human

免疫原

205-234 aa

靶点

This SDHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the C-terminal region of human SDHB.

亚型

Rabbit Ig

通用名

SDH, SDH1

基因ID

UniProt ID

功能

Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

总结

Complex II of the respiratory chain, which is specificallyinvolved in the oxidation of succinate, carries electrons from FADHto CoQ. The complex is composed of four nuclear-encoded subunitsand is localized in the mitochondrial inner membrane. Theiron-sulfur subunit is highly conserved and contains threecysteine-rich clusters which may comprise the iron-sulfur centersof the enzyme. Sporadic and familial mutations in this gene resultin paragangliomas and pheochromocytoma, and support a link betweenmitochondrial dysfunction and tumorigenesis.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

别名

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip, SDHB, SDH, SDH1

图像

SDHB Antibody (C-term) (Cat. APR07172G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SDHB antibody detected the SDHB protein (arrow).

说明书

数量

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