品牌 |
Leading Biology | 货号 |
APR07172G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SDHB antibody (C-term).
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分子量 |
31630 Da
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
205-234 aa
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靶点 |
This SDHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the C-terminal region of human SDHB.
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亚型 |
Rabbit Ig
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通用名 |
SDH, SDH1
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基因ID |
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UniProt ID |
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功能 |
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
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总结 |
Complex II of the respiratory chain, which is specificallyinvolved in the oxidation of succinate, carries electrons from FADHto CoQ. The complex is composed of four nuclear-encoded subunitsand is localized in the mitochondrial inner membrane. Theiron-sulfur subunit is highly conserved and contains threecysteine-rich clusters which may comprise the iron-sulfur centersof the enzyme. Sporadic and familial mutations in this gene resultin paragangliomas and pheochromocytoma, and support a link betweenmitochondrial dysfunction and tumorigenesis.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip, SDHB, SDH, SDH1
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图像 |
SDHB Antibody (C-term) (Cat. APR07172G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SDHB antibody detected the SDHB protein (arrow). |
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说明书 |
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数量 |
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