全部产品分类
品牌 |
Leading Biology | 货号 |
APR07635G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EBP antibody(C-term).
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分子量 |
26353 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
201-230 aa
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靶点 |
This EBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the C-terminal region of human EBP.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.
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总结 |
The protein encoded by this gene is an integral membraneprotein of the endoplasmic reticulum. It is a high affinity bindingprotein for the antiischemic phenylalkylamine Ca2+ antagonist[3H]emopamil and the photoaffinity label [3H]azidopamil. It issimilar to sigma receptors and may be a member of a superfamily ofhigh affinity drug-binding proteins in the endoplasmic reticulum ofdifferent tissues. This protein shares structural features withbacterial and eukaryontic drug transporting proteins. It has fourputative transmembrane segments and contains two conservedglutamate residues which may be involved in the transport ofcationic amphiphilics. Another prominent feature of this protein isits high content of aromatic amino acid residues (>23%) in itstransmembrane segments. These aromatic amino acid residues havebeen suggested to be involved in the drug transport by theP-glycoprotein. Mutations in this gene cause Chondrodysplasiapunctata 2 (CDPX2; also known as Conradi-Hunermann syndrome).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase, Cholestenol Delta-isomerase, Delta(8)-Delta(7) sterol isomerase, D8-D7 sterol isomerase, Emopamil-binding protein, EBP
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图像 |
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说明书 |
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数量 |
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