全部产品分类
品牌 |
Leading Biology | 货号 |
APG02451G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CB1 antibody(Center).
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分子量 |
52858 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
161-187 aa
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靶点 |
This CB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human CB1.
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亚型 |
Rabbit Ig
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通用名 |
CNR
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基因ID |
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UniProt ID |
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功能 |
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
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总结 |
This gene encodes one of two cannabinoid receptors. Thecannabinoids, principally delta-9-tetrahydrocannabinol andsynthetic analogs, are psychoactive ingredients of marijuana. Thecannabinoid receptors are members of the guanine-nucleotide-bindingprotein (G-protein) coupled receptor family, which inhibitadenylate cyclase activity in a dose-dependent, stereoselective andpertussis toxin-sensitive manner. The two receptors have been foundto be involved in the cannabinoid-induced CNS effects (includingalterations in mood and cognition) experienced by users ofmarijuana. Multiple transcript variants encoding two differentprotein isoforms have been described for this gene. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR
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图像 |
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说明书 |
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数量 |
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