全部产品分类
品牌 |
Leading Biology | 货号 |
APR13927G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality USH1C antibody(N-term).
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分子量 |
62211 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin (By similarity). Detected at the tip of cochlear hair cell stereocilia.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
1-30 aa
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靶点 |
This USH1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USH1C.
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亚型 |
Rabbit Ig
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通用名 |
AIE75
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基因ID |
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UniProt ID |
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功能 |
Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity).
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总结 |
This gene encodes a scaffold protein that functions in theassembly of Usher protein complexes. The protein contains PDZdomains, a coiled-coil region with a bipartite nuclear localizationsignal and a PEST degradation sequence. Defects in this gene arethe cause of Usher syndrome type 1C and non-syndromic sensorineuraldeafness autosomal recessive type 18. Multiple transcript variantsencoding different isoforms have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Harmonin, Antigen NY-CO-38/NY-CO-37, Autoimmune enteropathy-related antigen AIE-75, Protein PDZ-73, Renal carcinoma antigen NY-REN-3, Usher syndrome type-1C protein, USH1C, AIE75
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图像 |
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说明书 |
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数量 |
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