全部产品分类
品牌 |
Leading Biology | 货号 |
APR08704G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NDUFV1 antibody(N-term).
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分子量 |
50817 Da
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
21-50 aa
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靶点 |
This NDUFV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human NDUFV1.
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亚型 |
Rabbit Ig
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通用名 |
UQOR1
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基因ID |
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UniProt ID |
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功能 |
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
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总结 |
The mitochondrial respiratory chain provides energy tocells via oxidative phosphorylation and consists of fourmembrane-bound electron-transporting protein complexes (I-IV) andan ATP synthase (complex V). This gene encodes a 51 kDa subunit ofthe NADH:ubiquinone oxidoreductase complex I; a large complex withat least 45 nuclear and mitochondrial encoded subunits thatliberates electrons from NADH and channels them to ubiquinone. Thissubunit carries the NADH-binding site as well as flavinmononucleotide (FMN)- and Fe-S-biding sites. Defects in complex Iare a common cause of mitochondrial dysfunction; a syndrome thatoccurs in approximately 1 in 10,000 live births. Mitochondrialcomplex I deficiency is linked to myopathies, encephalomyopathies,and neurodegenerative disorders such as Parkinson's disease andLeigh syndrome. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, Complex I-51kD, CI-51kD, NADH dehydrogenase flavoprotein 1, NADH-ubiquinone oxidoreductase 51 kDa subunit, NDUFV1, UQOR1
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图像 |
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说明书 |
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数量 |
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