全部产品分类
品牌 |
Leading Biology | 货号 |
APR07778G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HMOX2 antibody (N-term).
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分子量 |
36033 Da
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细胞定位 |
Antigen Cellular Localization:
Microsome. Endoplasmic reticulum.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
24-52 aa
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靶点 |
This HMOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human HMOX2.
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亚型 |
Rabbit Ig
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通用名 |
HO2
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基因ID |
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UniProt ID |
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功能 |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
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总结 |
Heme oxygenase, an essential enzyme in heme catabolism,cleaves heme to form biliverdin, which is subsequently converted tobilirubin by biliverdin reductase, and carbon monoxide, a putativeneurotransmitter. Heme oxygenase activity is induced by itssubstrate heme and by various nonheme substances. Heme oxygenaseoccurs as 2 isozymes, an inducible heme oxygenase-1 and aconstitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the hemeoxygenase family. Alternative splice variants encoding the sameprotein have been identified at this locus.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Heme oxygenase 2, HO-2, HMOX2, HO2
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图像 |
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说明书 |
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数量 |
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