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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > MSX1 Antibody (Center)

MSX1 Antibody (Center)

货号 货期 规格 / 价格 询价
AMM06496G 100 μl / ¥4950

MSX1 Antibody (Center)

品牌

Leading Biology

货号

AMM06496G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MSX1 antibody (Center).

分子量

31496 Da

细胞定位

Antigen Cellular Localization: Nucleus.

宿主

Rabbit

种属反应性

Human, Mouse

免疫原

111-138 aa

靶点

This MSX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human MSX1.

亚型

Rabbit Ig

通用名

HOX7

基因ID

UniProt ID

功能

Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity.

总结

This gene encodes a member of the muscle segment homeoboxgene family. The encoded protein functions as a transcriptionalrepressor during embryogenesis through interactions with componentsof the core transcription complex and other homeoproteins. It mayalso have roles in limb-pattern formation, craniofacialdevelopment, particularly odontogenesis, and tumor growthinhibition. Mutations in this gene, which was once known ashomeobox 7, have been associated with nonsyndromic cleft lip withor without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome,and autosomoal dominant hypodontia.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

IF, WB, E

稀释方法

WB~~1:1000 IF~~1:200

别名

Homeobox protein MSX-1, Homeobox protein Hox-7, Msh homeobox 1-like protein, MSX1, HOX7

图像

Anti-MSX1 Antibody (Center)at 1:2000 dilution + mouse spleen lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 31 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Fluorescent image of U251 cell stained with MSX1 Antibody (Center)( AMM06496G).U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with MSX1 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor? 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor? 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃).MSX1 immunoreactivity is localized to Nucleus significantly.

MSX1 Antibody (Center)(Cat. AMM06496G) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the MSX1 antibody detected the MSX1 protein (arrow).

说明书

数量

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