全部产品分类
品牌 |
Leading Biology | 货号 |
APR08048G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ITPA antibody (C-term).
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分子量 |
21446 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03148, ECO:0000269|PubMed:11278832}
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
149-178 aa
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靶点 |
This ITPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the C-terminal region of human ITPA.
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亚型 |
Rabbit Ig
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通用名 |
C20orf37
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基因ID |
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UniProt ID |
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功能 |
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
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总结 |
The protein encoded by this gene hydrolyzes inosinetriphosphate and deoxyinosine triphosphate to the monophosphatenucleotide and diphosphate. The encoded protein, which is a memberof the HAM1 NTPase protein family, is found in the cytoplasm andacts as a homodimer. Defects in the encoded protein can result ininosine triphosphate pyrophosphorylase deficiency. Two transcriptvariants encoding two different isoforms have been found for thisgene. Also, at least two other transcript variants have beenidentified which are probably regulatory rather thanprotein-coding.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Inosine triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, ITPase {ECO:0000255|HAMAP-Rule:MF_03148}, Inosine triphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, 36119 {ECO:0000255|HAMAP-Rule:MF_03148}, Non-canonical purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Non-standard purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate diphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, NTPase {ECO:0000255|HAMAP-Rule:MF_03148}, Putative oncogene protein hlc14-06-p, ITPA {ECO:0000255|HAMAP-Rule:MF_03148}, C20orf37
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图像 |
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说明书 |
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数量 |
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