品牌 |
Leading Biology | 货号 |
APR10691G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VAPB antibody (C-term).
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分子量 |
27228 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein Note=Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
171-200 aa
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靶点 |
This VAPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the C-terminal region of human VAPB.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
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总结 |
The protein encoded by this gene is a type IV membraneprotein found in plasma and intracellular vesicle membranes. Theencoded protein is found as a homodimer and as a heterodimer withVAPA. This protein also can interact with VAMP1 and VAMP2 and maybe involved in vesicle trafficking.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Vesicle-associated membrane protein-associated protein B/C, VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C, VAPB
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图像 |
VAPB Antibody (C-term)(Cat. APR10691G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the VAPB antibody detected the VAPB protein (arrow). |
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说明书 |
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数量 |
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