全部产品分类
品牌 |
Leading Biology | 货号 |
AMM04545G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FH antibody (N-term).
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分子量 |
54637 Da
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细胞定位 |
Antigen Cellular Localization:
Isoform Mitochondrial: Mitochondrion.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
107-135 aa
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靶点 |
This FH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-135 amino acids from the N-terminal region of human FH.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Also acts as a tumor suppressor.
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总结 |
The protein encoded by this gene is an enzymatic componentof the tricarboxylic acid (TCA) cycle, or Krebs cycle, andcatalyzes the formation of L-malate from fumarate. It exists inboth a cytosolic form and an N-terminal extended form, differingonly in the translation start site used. The N-terminal extendedform is targeted to the mitochondrion, where the removal of theextension generates the same form as in the cytoplasm. It issimilar to some thermostable class II fumarases and functions as ahomotetramer. Mutations in this gene can cause fumarase deficiencyand lead to progressive encephalopathy.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Fumarate hydratase, mitochondrial, Fumarase, FH
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图像 |
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说明书 |
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数量 |
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