全部产品分类
品牌 |
Leading Biology | 货号 |
APR15246G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CAMSAP3 antibody (N-term).
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分子量 |
134750 Da
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细胞定位 |
Antigen Cellular Localization:
Cell junction, adherens junction. Cytoplasm. Cytoplasm, cytoskeleton. Note=Scattered in the cytoplasm, associated with the minus-end of microtubules and also detected at the centrosomes. Localizes along zonula adherens only at mature cell-cell contacts
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
103-131 aa
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靶点 |
This CAMSAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the N-terminal region of human CAMSAP3.
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亚型 |
Rabbit Ig
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通用名 |
KIAA1543
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基因ID |
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UniProt ID |
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功能 |
Microtubule minus-end binding protein that acts as a regulator of non-centrosomal microtubule dynamics and organization. Specifically required for the biogenesis and the maintenance of zonula adherens by anchoring the minus-end of microtubules to zonula adherens and by recruiting the kinesin KIFC3 to those junctional sites. May regulate the nucleation and the polymerization of microtubules. Indirectly, through the microtubule cytoskeleton, may regulate the organization of cellular organelles including the Golgi and the early endosomes.
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总结 |
Microtubule minus-end binding protein that acts as a regulator of microtubule dynamics. Specifically required for zonula adherens biogenesis and maintenance by anchoring microtubules at their minus-ends to zonula adherens, leading to recruit KIFC3 kinesin to junctional site.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Calmodulin-regulated spectrin-associated protein 3, Protein Nezha, CAMSAP3, KIAA1543
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图像 |
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说明书 |
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数量 |
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