品牌 |
Leading Biology | 货号 |
APG01851G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AMBRA1 antibody (N-term).
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分子量 |
142507 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasmic vesicle, autophagosome. Note=Localizes also to discrete punctae along the ciliary axoneme.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
27-55 aa
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靶点 |
This AMBRA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human AMBRA1.
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亚型 |
Rabbit Ig
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通用名 |
KIAA1736
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基因ID |
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UniProt ID |
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功能 |
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity).
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总结 |
AMBRA1 regulates autophagy and development of the nervous system. This protein is involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
Activating molecule in BECN1-regulated autophagy protein 1, AMBRA1, KIAA1736
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图像 |
Western blot analysis of AMBRA1 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). AMBRA1(arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with AMBRA1 antibody (N-term) (Cat. APG01851G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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