全部产品分类
品牌 |
Leading Biology | 货号 |
AMR09488G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PPP1R3B antibody (C-term).
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分子量 |
32695 Da
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
205-231 aa
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靶点 |
This PPP1R3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human PPP1R3B.
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亚型 |
Rabbit Ig
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通用名 |
PPP1R4
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基因ID |
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UniProt ID |
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功能 |
Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity).
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总结 |
The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA;MIM 176875) is regulated by targeting subunits, such as PP1R3B.PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e.,inactivates) glycogen phosphorylase (see PYGL; MIM 232700) andenhances the rate at which it activates glycogen synthase (seeGYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[suppliedby OMIM].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Protein phosphatase 1 regulatory subunit 3B, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, Protein phosphatase 1 regulatory subunit 4, PP1 subunit R4, Protein phosphatase 1 subunit GL, PTG, PPP1R3B, PPP1R4
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图像 |
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说明书 |
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数量 |
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