全部产品分类
品牌 |
Leading Biology | 货号 |
AMM08208G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TIPRL antibody (C-term).
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分子量 |
31444 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
189-218 aa
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靶点 |
This TIPRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human TIPRL.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May be a allosteric regulator of serine/threonine- protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
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总结 |
TIPRL is an inhibitory regulator of protein phosphatase-2A(PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), andPP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed17384681]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
TIP41-like protein, Putative MAPK-activating protein PM10, Type 2A-interacting protein, TIP, TIPRL
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图像 |
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说明书 |
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数量 |
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