全部产品分类
品牌 |
Leading Biology | 货号 |
APR07770G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HMGCL antibody (N-term).
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分子量 |
34360 Da
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion matrix. Peroxisome. Note=Unprocessed form is peroxisomal
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
71-99 aa
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靶点 |
This HMGCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human HMGCL.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
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总结 |
The protein encoded by this gene belongs to the HMG-CoAlyase family. It is a mitochondrial enzyme that catalyzes the finalstep of leucine degradation and plays a key role in ketone bodyformation. Mutations in this gene are associated with HMG-CoA lyasedeficiency. Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Hydroxymethylglutaryl-CoA lyase, mitochondrial, HL, HMG-CoA lyase, 3-hydroxy-3-methylglutarate-CoA lyase, HMGCL
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图像 |
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说明书 |
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数量 |
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