品牌 |
Leading Biology | 货号 |
APG01960G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AQP1 antibody (C-term).
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分子量 |
28526 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
241-269 aa
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靶点 |
This AQP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human AQP1.
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亚型 |
Rabbit Ig
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通用名 |
CHIP28
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基因ID |
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UniProt ID |
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功能 |
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
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总结 |
Aquaporins are a family of small integral membraneproteins related to the major intrinsic protein (MIP or AQP0). Thisgene encodes an aquaporin which functions as a molecular waterchannel protein. It is a homotetramer with 6 bilayer spanningdomains and N-glycosylation sites. The protein physically resembleschannel proteins and is abundant in erythrocytes and renal tubes.The gene encoding this aquaporin is a possible candidate fordisorders involving imbalance in ocular fluid movement. Severaltranscript variants encoding different isoforms have been found forthis gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Aquaporin-1, AQP-1, Aquaporin-CHIP, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule, AQP1, CHIP28
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图像 |
AQP1 Antibody (C-term) (Cat. APG01960G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).
AQP1 Antibody (C-term) (Cat. APG01960G) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the AQP1 antibody detected the AQP1 protein (arrow). |
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说明书 |
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数量 |
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