全部产品分类
品牌 |
Leading Biology | 货号 |
AMM08098G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TBC1D10B antibody (C-term).
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分子量 |
87199 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Note=In melanocytes, located at the periphery of cells
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
781-808 aa
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靶点 |
This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, AND RAB35. Does not act on RAB2A and RAB6A.
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总结 |
Small G proteins of the RAB family (see MIM 179508)function in intracellular vesicle trafficking by switching from theGTP-bound state to the GDP-bound state with the assistance ofguanine nucleotide exchange factors (GEFs; see MIM 609700) andGTPase-activating proteins (GAPs). TBC1D10B functions as a GAP forseveral proteins of the Rab family (Ishibashi et al., 2009 [PubMed19077034]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
TBC1 domain family member 10B, Rab27A-GAP-beta, TBC1D10B
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图像 |
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说明书 |
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数量 |
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