全部产品分类
品牌 |
Leading Biology | 货号 |
AMM06704G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NKX2-5 antibody (Center).
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分子量 |
34918 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
2-5 aa
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靶点 |
This NKX2-5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the Central region of human NKX2-5.
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亚型 |
Rabbit Ig
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通用名 |
CSX, NKX2.5, NKX2E
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基因ID |
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UniProt ID |
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功能 |
Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.
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总结 |
This gene encodes a homeobox-containing transcriptionfactor. This transcription factor functions in heart formation anddevelopment. Mutations in this gene cause atrial septal defect withatrioventricular conduction defect, and also tetralogy of Fallot,which are both heart malformation diseases. Mutations in this genecan also cause congenital hypothyroidism non-goitrous type 5, anon-autoimmune condition. Alternative splicing results in multipletranscript variants.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:2000
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别名 |
Homeobox protein Nkx-25, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E, NKX2-5, CSX, NKX25, NKX2E
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图像 |
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说明书 |
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数量 |
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