全部产品分类
品牌 |
Leading Biology | 货号 |
AMM06568G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NCDN antibody (N-term).
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分子量 |
78864 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Cell projection, dendrite. Note=Localizes to somatic regions of neurons
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
114-144 aa
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靶点 |
This NCDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-144 amino acids from the N-terminal region of human NCDN.
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亚型 |
Rabbit Ig
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通用名 |
KIAA0607
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基因ID |
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UniProt ID |
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功能 |
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (By similarity). Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
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总结 |
This gene encodes a leucine-rich cytoplasmic protein,which is highly similar to a mouse protein that negativelyregulates Ca/calmodulin-dependent protein kinase II phosphorylationand may be essential for spatial learning processes. Severalalternatively spliced transcript variants of this gene have beendescribed.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Neurochondrin, NCDN, KIAA0607
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图像 |
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说明书 |
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数量 |
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