全部产品分类
品牌 |
Leading Biology | 货号 |
APG01520G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ACSL3 antibody (C-term).
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分子量 |
80420 Da
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
528-556 aa
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靶点 |
This ACSL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-556 amino acids from the C-terminal region of human ACSL3.
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亚型 |
Rabbit Ig
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通用名 |
ACS3, FACL3, LACS3
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基因ID |
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UniProt ID |
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功能 |
Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins).
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总结 |
The protein encoded by this gene is an isozyme of thelong-chain fatty-acid-coenzyme A ligase family. Although differingin substrate specificity, subcellular localization, and tissuedistribution, all isozymes of this family convert free long-chainfatty acids into fatty acyl-CoA esters, and thereby play a key rolein lipid biosynthesis and fatty acid degradation. This isozyme ishighly expressed in brain, and preferentially utilizes myristate,arachidonate, and eicosapentaenoate as substrates. The amino acidsequence of this isozyme is 92% identical to that of rat homolog.Two transcript variants encoding the same protein have been foundfor this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Long-chain-fatty-acid--CoA ligase 3, Long-chain acyl-CoA synthetase 3, LACS 3, ACSL3, ACS3, FACL3, LACS3
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图像 |
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说明书 |
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数量 |
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