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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > NKIRAS2 Antibody (Center)

NKIRAS2 Antibody (Center)

货号 货期 规格 / 价格 询价
APR17579G 100 μl / ¥4950

NKIRAS2 Antibody (Center)

品牌

Leading Biology

货号

APR17579G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NKIRAS2 antibody (Center).

分子量

21508 Da

细胞定位

Antigen Cellular Localization: Cytoplasm.

宿主

Rabbit

种属反应性

Human

免疫原

36-64 aa

靶点

This NKIRAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the Central region of human NKIRAS2.

亚型

Rabbit Ig

通用名

KBRAS2

基因ID

UniProt ID

功能

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF- kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).

总结

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB (By similarity).

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

别名

NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2, NKIRAS2, KBRAS2

图像

NKIRAS2 Antibody (Center) (Cat. APR17579G) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the NKIRAS2 antibody detected the NKIRAS2 protein (arrow).

说明书

数量

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