全部产品分类
品牌 |
Leading Biology | 货号 |
AMM07211G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PKD2L1 antibody (N-term).
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分子量 |
91982 Da
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细胞定位 |
Antigen Cellular Localization:
Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein Endoplasmic reticulum. Note=Interaction with PKD1 or PKD1L3 is required for localization to the cell membrane
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
37-65 aa
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靶点 |
This PKD2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human PKD2L1.
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亚型 |
Rabbit Ig
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通用名 |
PKD2L, PKDL, TRPP3
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基因ID |
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UniProt ID |
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功能 |
Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.
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总结 |
PKD2L1 is a member of the polycystin proteinfamily. The encoded protein contains multiple transmembranedomains, and cytoplasmic N- and C-termini. The protein may be anintegral membrane protein involved in cell-cell/matrixinteractions. This protein functions as a calcium-regulatednonselective cation channel. Alternative splice variants have beendescribed but their full length sequences have not been determined.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1, PKD2L1, PKD2L, PKDL, TRPP3
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图像 |
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说明书 |
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数量 |
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