全部产品分类
品牌 |
Leading Biology | 货号 |
APR14030G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ZFPM2 antibody (C-term).
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分子量 |
128159 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
883-911 aa
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靶点 |
This ZFPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 883-911 amino acids from the C-terminal region of human ZFPM2.
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亚型 |
Rabbit Ig
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通用名 |
FOG2, ZNF89B
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基因ID |
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UniProt ID |
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功能 |
Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2 (By similarity).
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总结 |
The zinc finger protein encoded by this gene is a widelyexpressed member of the FOG family of transcription factors. Thefamily members modulate the activity of GATA family proteins, whichare important regulators of hematopoiesis and cardiogenesis inmammals. It has been demonstrated that the protein can bothactivate and down-regulate expression of GATA-target genes,suggesting different modulation in different promoter contexts. Arelated mRNA suggests an alternatively spliced product but thisinformation is not yet fully supported by the sequence. [providedby RefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Zinc finger protein ZFPM2, Friend of GATA protein 2, FOG-2, Friend of GATA 2, hFOG-2, Zinc finger protein 89B, Zinc finger protein multitype 2, ZFPM2, FOG2, ZNF89B
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图像 |
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说明书 |
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数量 |
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