品牌 |
Leading Biology | 货号 |
AMM07111G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PFN2 antibody (C-term).
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分子量 |
15046 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
110-139 aa
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靶点 |
This PFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of human PFN2.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
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总结 |
The protein encoded by this gene is a ubiquitous actinmonomer-binding protein belonging to the profilin family. It isthought to regulate actin polymerization in response toextracellular signals. There are two alternatively splicedtranscript variants encoding different isoforms described for thisgene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Profilin-2, Profilin II, PFN2
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图像 |
PFN2 Antibody (C-term) (Cat. AMM07111G) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the PFN2 antibody detected the PFN2 protein (arrow). |
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说明书 |
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数量 |
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