全部产品分类
品牌 |
Leading Biology | 货号 |
APR16814G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IHH antibody (N-term).
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分子量 |
45251 Da
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细胞定位 |
Antigen Cellular Localization:
Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface. Cell membrane.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
51-80 aa
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靶点 |
This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human IHH.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).
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总结 |
This gene encodes a member of the hedgehog family ofsecreted signaling molecules. Hedgehog proteins are essentialregulators of a variety of developmental processes includinggrowth, patterning and morphogenesis. The encoded proteinspecifically plays a role in bone growth an differentiation.Mutations in this gene are the cause of brachydactyly type A1 whichis characterized by shortening or malformation of the phalanges.Mutations in this gene are also the cause of acrocapitofemoraldysplasia.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
Indian hedgehog protein, IHH, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product, IHH
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图像 |
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说明书 |
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数量 |
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