品牌 |
Leading Biology | 货号 |
APR17413G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Mouse Clk4 antibody (N-term).
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分子量 |
57345 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Mouse
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免疫原 |
49-77 aa
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靶点 |
This Mouse Clk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of mouse Clk4.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
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总结 |
Phosphorylates serine-and arginine-rich (SR) proteins of the spliceosomal complex may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines. Required for the regulation of alternative splicing of MAPT/TAU.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Dual specificity protein kinase CLK4, CDC-like kinase 4, Clk4
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图像 |
Mouse Clk4 Antibody (N-term) (Cat. APR17413G) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Clk4 antibody detected the Clk4 protein (arrow). |
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说明书 |
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数量 |
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