全部产品分类
品牌 |
Leading Biology | 货号 |
APR09073G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PGF antibody (Center).
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分子量 |
24789 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
120-148 aa
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靶点 |
This PGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human PGF.
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亚型 |
Rabbit Ig
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通用名 |
PGFL, PLGF
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基因ID |
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UniProt ID |
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功能 |
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
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总结 |
The PGF gene encodes placenta growth factor, a homolog ofvascular endothelial growth factor (VEGFA; MIM 192240), thatselectively binds to VEGFR1 (FLT1; MIM 165070) and is involved inangiogenesis (Fischer et al., 2007 [PubMed 17981115]; Bais et al.,2010 [PubMed 20371352]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
Placenta growth factor, PlGF, PGF, PGFL, PLGF
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图像 |
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说明书 |
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数量 |
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