全部产品分类
品牌 |
Leading Biology | 货号 |
APR08831G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NRF1 antibody (Center).
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分子量 |
53541 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
226-255 aa
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靶点 |
This NRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-255 amino acids from the Central region of human NRF1.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
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总结 |
This gene encodes a protein that homodimerizes andfunctions as a transcription factor which activates the expressionof some key metabolic genes regulating cellular growth and nucleargenes required for respiration, heme biosynthesis, andmitochondrial DNA transcription and replication. The protein hasalso been associated with the regulation of neurite outgrowth.Alternate transcriptional splice variants, which encode the sameprotein, have been characterized. Additional variants encodingdifferent protein isoforms have been described but they have notbeen fully characterized. Confusion has occurred in bibliographicdatabases due to the shared symbol of NRF1 for this gene and for'nuclear factor (erythroid-derived 2)-like 1' which has an officialsymbol of NFE2L1.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal, NRF1
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图像 |
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说明书 |
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数量 |
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