全部产品分类
品牌 |
Leading Biology | 货号 |
APR08914G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PADI2 antibody (C-term).
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分子量 |
75564 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
557-586 aa
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靶点 |
This PADI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-586 amino acids from the C-terminal region of human PADI2.
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亚型 |
Rabbit Ig
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通用名 |
KIAA0994, PDI2
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the deimination of arginine residues of proteins.
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总结 |
This gene encodes a member of the peptidyl argininedeiminase family of enzymes, which catalyze the post-translationaldeimination of proteins by converting arginine residues intocitrullines in the presence of calcium ions. The family membershave distinct substrate specificities and tissue-specificexpression patterns. The type II enzyme is the most widelyexpressed family member. Known substrates for this enzyme includemyelin basic protein in the central nervous system and vimentin inskeletal muscle and macrophages. This enzyme is thought to play arole in the onset and progression of neurodegenerative humandisorders, including Alzheimer disease and multiple sclerosis, andit has also been implicated in glaucoma pathogenesis. This geneexists in a cluster with four other paralogous genes. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Protein-arginine deiminase type-2, PAD-H19, Peptidylarginine deiminase II, Protein-arginine deiminase type II, PADI2, KIAA0994, PDI2
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图像 |
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说明书 |
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数量 |
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