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APG10L Antibody (C-term S116)

APG01908G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APG01908G		100 μl / ￥4950

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APG10L Antibody (C-term S116)

品牌	Leading Biology	货号	APG01908G
产品分类	Polyclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APG10L antibody (C-term S116).
分子量	25279 Da
细胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
种属反应性	Human
免疫原	96-121 aa
靶点	This APG10L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-121 amino acids from the C-terminal region of human APG10L.
亚型	Rabbit Ig
通用名	APG10L
基因ID	83734
UniProt ID	Q9H0Y0
功能	E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis.
总结	Autophagy is a process for the bulk degradation ofcytosolic compartments by lysosomes. ATG10 is an E2-like enzymeinvolved in 2 ubiquitin-like modifications essential forautophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261)conjugation and modification of a soluble form of MAP-LC3(MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to amembrane-bound form (Nemoto et al., 2003 [PubMed12890687]).
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC-P, E
稀释方法	WB~~1:1000 IHC-P~~1:10~50
别名	Ubiquitin-like-conjugating enzyme ATG10, 632-, Autophagy-related protein 10, APG10-like, ATG10, APG10L
图像	APG10L Antibody (C-term S116) (Cat. APG01908G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the APG10L antibody detected the APG10L protein (arrow). Western blot analysis of APG10L (arrow) using rabbit polyclonal APG10L Antibody (C-term S116) (Cat. APG01908G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the APG10L gene. APG10L Antibody (C-term S116) (Cat. APG01908G)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ANKS1B APG10L Antibody (C-term S116) for immunohistochemistry. Clinical relevance has not been evaluated.
说明书	Product Datasheet Protocol
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