全部产品分类
品牌 |
Leading Biology | 货号 |
APR14417G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality USO1 antibody (C-term).
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分子量 |
107895 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Note=Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
932-960 aa
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靶点 |
This USO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 932-960 amino acids from the C-terminal region of human USO1.
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亚型 |
Rabbit Ig
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通用名 |
VDP
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基因ID |
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UniProt ID |
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功能 |
General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
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总结 |
The protein encoded by this gene is a peripheral membraneprotein which recycles between the cytosol and the Golgi apparatusduring interphase. It is regulated by phosphorylation:dephosphorylated protein associates with the Golgi membrane anddissociates from the membrane upon phosphorylation. Ras-associatedprotein 1 recruits this protein to coat protein complex II (COPII)vesicles during budding from the endoplasmic reticulum, where itinteracts with a set of COPII vesicle-associated SNAREs to form acis-SNARE complex that promotes targeting to the Golgi apparatus.Transport from the ER to the cis/medial Golgi compartments requiresthe action of this gene product, GM130 and giantin in a sequentialmanner.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
General vesicular transport factor p115, Protein USO1 homolog, Transcytosis-associated protein, TAP, Vesicle-docking protein, USO1, VDP
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图像 |
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说明书 |
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数量 |
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