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ARHGDIB Antibody (C-term)

APR14308G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR14308G		100 μl / ￥4950

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ARHGDIB Antibody (C-term)

品牌	Leading Biology	货号	APR14308G
产品分类	Polyclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARHGDIB antibody (C-term).
分子量	22988 Da
细胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
种属反应性	Human
免疫原	160-188 aa
靶点	This ARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the C-terminal region of human ARHGDIB.
亚型	Rabbit Ig
通用名	GDIA2, GDID4, RAP1GN1
基因ID	397
UniProt ID	P52566
功能	Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
总结	Members of the Rho (or ARH) protein family (see MIM165390) and other Ras-related small GTP-binding proteins (see MIM179520) are involved in diverse cellular events, including cellsignaling, proliferation, cytoskeletal organization, and secretion.The GTP-binding proteins are active only in the GTP-bound state. Atleast 3 classes of proteins tightly regulate cycling between theGTP-bound and GDP-bound states: GTPase-activating proteins (GAPs),guanine nucleotide-releasing factors (GRFs), and GDP-dissociationinhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rateof GDP dissociation from Ras-like GTPases (summary by Scherle etal., 1993 [PubMed 8356058]).
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC-P, E
稀释方法	WB~~1:1000 IHC-P~~1:10~50
别名	Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta, ARHGDIB, GDIA2, GDID4, RAP1GN1
图像	ARHGDIB Antibody (C-term) (Cat. APR14308G) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ARHGDIB antibody detected the ARHGDIB protein (arrow). ARHGDIB Antibody (C-term) (Cat. APR14308G)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ARHGDIB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
说明书	Product Datasheet Protocol
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