全部产品分类
品牌 |
Leading Biology | 货号 |
AMM06171G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KCNV2 antibody (C-term).
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分子量 |
62459 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
478-507 aa
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靶点 |
This KCNV2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-507 amino acids from the C-terminal region of human KCNV2.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
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总结 |
Voltage-gated potassium (Kv) channels represent the mostcomplex class of voltage-gated ion channels from both functionaland structural standpoints. Their diverse functions includeregulating neurotransmitter release, heart rate, insulin secretion,neuronal excitability, epithelial electrolyte transport, smoothmuscle contraction, and cell volume. This gene encodes a member ofthe potassium voltage-gated channel subfamily V. This member isidentified as a 'silent subunit', and it does not formhomomultimers, but forms heteromultimers with several othersubfamily members. Through obligatory heteromerization, it exerts afunction-altering effect on other potassium channel subunits. Thisprotein is strongly expressed in pancreas and has a weakerexpression in several other tissues.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
Potassium voltage-gated channel subfamily V member 2, Voltage-gated potassium channel subunit Kv82, KCNV2
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图像 |
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说明书 |
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数量 |
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