全部产品分类
品牌 |
Leading Biology | 货号 |
APR10328G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SULF2 antibody (C-term).
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分子量 |
100455 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum. Golgi apparatus, Golgi stack. Cell surface Note=Also localized on the cell surface.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
824-852 aa
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靶点 |
This SULF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 824-852 amino acids from the C-terminal region of human SULF2.
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亚型 |
Rabbit Ig
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通用名 |
KIAA1247
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基因ID |
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UniProt ID |
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功能 |
Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
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总结 |
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Extracellular sulfatase Sulf-2, hSulf-2, 316-, SULF2, KIAA1247
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图像 |
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说明书 |
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数量 |
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