全部产品分类
品牌 |
Leading Biology | 货号 |
APR15978G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FGFRL1 antibody (N-term).
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分子量 |
54537 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
131-160 aa
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靶点 |
This FGFRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-160 amino acids from the N-terminal region of human FGFRL1.
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亚型 |
Rabbit Ig
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通用名 |
FGFR5, FHFR
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基因ID |
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UniProt ID |
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功能 |
Has a negative effect on cell proliferation.
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总结 |
The protein encoded by this gene is a member of thefibroblast growth factor receptor (FGFR) family, where amino acidsequence is highly conserved between members and throughoutevolution. FGFR family members differ from one another in theirligand affinities and tissue distribution. A full-lengthrepresentative protein would consist of an extracellular region,composed of three immunoglobulin-like domains, a single hydrophobicmembrane-spanning segment and a cytoplasmic tyrosine kinase domain.The extracellular portion of the protein interacts with fibroblastgrowth factors, setting in motion a cascade of downstream signals,ultimately influencing mitogenesis and differentiation. A markeddifference between this gene product and the other family membersis its lack of a cytoplasmic tyrosine kinase domain. The result isa transmembrane receptor that could interact with other familymembers and potentially inhibit signaling. Multiple alternativelyspliced transcript variants encoding the same isoform have beenfound for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P, WB, E
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稀释方法 |
IHC-P~~1:10~50
WB~~1:1000
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别名 |
Fibroblast growth factor receptor-like 1, FGF receptor-like protein 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5, FGFR-5, FGFRL1, FGFR5, FHFR
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图像 |
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说明书 |
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数量 |
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