全部产品分类
品牌 |
Leading Biology | 货号 |
APR15944G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FCN3 antibody (C-term).
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分子量 |
32903 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted. Note=Found in blood plasma, bronchus, alveolus and bile duct
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
214-243 aa
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靶点 |
This FCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of human FCN3.
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亚型 |
Rabbit Ig
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通用名 |
FCNH, HAKA1
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基因ID |
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UniProt ID |
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功能 |
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota.
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总结 |
Ficolins are a group of proteins which consist of acollagen-like domain and a fibrinogen-like domain. In human serum,there are two types of ficolins, both of which have lectinactivity. The protein encoded by this gene is a thermolabilebeta-2-macroglycoprotein found in all human serum and is a memberof the ficolin/opsonin p35 lectin family. The protein, which wasinitially identified based on its reactivity with sera frompatients with systemic lupus erythematosus, has been shown to havea calcium-independent lectin activity. The protein can activate thecomplement pathway in association with MASPs and sMAP, therebyaiding in host defense through the activation of the lectinpathway. Alternative splicing occurs at this locus and twovariants, each encoding a distinct isoform, have been identified.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50
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别名 |
Ficolin-3, Collagen/fibrinogen domain-containing lectin 3 p35, Collagen/fibrinogen domain-containing protein 3, Hakata antigen, FCN3, FCNH, HAKA1
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图像 |
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说明书 |
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数量 |
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