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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > SCP2 Antibody (N-term)

SCP2 Antibody (N-term)

货号 货期 规格 / 价格 询价
AMR09841G 100 μl / ¥4950

SCP2 Antibody (N-term)

品牌

Leading Biology

货号

AMR09841G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCP2 antibody (N-term).

分子量

58994 Da

细胞定位

Antigen Cellular Localization: Cytoplasm. Mitochondrion. Note=Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues Isoform SCP2: Mitochondrion.

宿主

Rabbit

种属反应性

Human

免疫原

14-43 aa

靶点

This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human SCP2.

亚型

Rabbit Ig

基因ID

UniProt ID

功能

Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.

总结

This gene encodes two proteins: sterol carrier protein X(SCPx) and sterol carrier protein 2 (SCP2), as a result oftranscription initiation from 2 independently regulated promoters.The transcript initiated from the proximal promoter encodes thelonger SCPx protein, and the transcript initiated from the distalpromoter encodes the shorter SCP2 protein, with the 2 proteinssharing a common C-terminus. Evidence suggests that the SCPxprotein is a peroxisome-associated thiolase that is involved in theoxidation of branched chain fatty acids, while the SCP2 protein isthought to be an intracellular lipid transfer protein. This gene ishighly expressed in organs involved in lipid metabolism, and mayplay a role in Zellweger syndrome, in which cells are deficient inperoxisomes and have impaired bile acid synthesis. Alternativesplicing of this gene produces multiple transcript variants, someencoding different isoforms.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

WB~~1:1000 IHC-P~~1:10~50

别名

Non-specific lipid-transfer protein, NSL-TP, Propanoyl-CoA C-acyltransferase, SCP-chi, SCPX, Sterol carrier protein 2, SCP-2, Sterol carrier protein X, SCP-X, SCP2

图像

SCP2 Antibody (N-term) (Cat. AMR09841G) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the SCP2 antibody detected the SCP2 protein (arrow).

SCP2 Antibody (N-term) (Cat. AMR09841G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SCP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

说明书

数量

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