品牌 |
Leading Biology | 货号 |
APR11753G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DLL3 antibody (C-term).
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分子量 |
64618 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
545-573 aa
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靶点 |
This DLL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 545-573 amino acids from the C-terminal region of human DLL3.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
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总结 |
This gene encodes a member of the delta protein ligandfamily. This family functions as Notch ligands that arecharacterized by a DSL domain, EGF repeats, and a transmembranedomain. Mutations in this gene cause autosomal recessivespondylocostal dysostosis 1. Two transcript variants encodingdistinct isoforms have been identified for this gene. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
IF~~1:10~50
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别名 |
Delta-like protein 3, Drosophila Delta homolog 3, Delta3, DLL3
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图像 |
DLL3 Antibody (C-term) (Cat. APR11753G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the DLL3 antibody detected the DLL3 protein (arrow).
DLL3 Antibody (C-term) (Cat. APR11753G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DLL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of DLL3 Antibody (C-term)( APR11753G) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
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说明书 |
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数量 |
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