全部产品分类
品牌 |
Leading Biology | 货号 |
APG02736G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality COX7A2L antibody (Center).
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分子量 |
12615 Da
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion inner membrane.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
37-65 aa
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靶点 |
This COX7A2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the Central region of human COX7A2L.
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亚型 |
Rabbit Ig
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通用名 |
COX7AR, COX7RP
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基因ID |
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UniProt ID |
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功能 |
Involved in the regulation of oxidative phosphorylation and energy metabolism (By similarity). Necessary for the assembly of mitochondrial respiratory supercomplex (By similarity).
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总结 |
Cytochrome c oxidase (COX), the terminal component of themitochondrial respiratory chain, catalyzes the electron transferfrom reduced cytochrome c to oxygen. This component is aheteromeric complex consisting of 3 catalytic subunits encoded bymitochondrial genes and multiple structural subunits encoded bynuclear genes. The mitochondrially-encoded subunits function inelectron transfer, and the nuclear-encoded subunits may function inthe regulation and assembly of the complex. This nuclear geneencodes a protein similar to polypeptides 1 and 2 of subunit VIIain the C-terminal region, and also highly similar to the mouseSig81 protein sequence. This gene is expressed in all tissues, andupregulated in a breast cancer cell line after estrogen treatment.It is possible that this gene represents a regulatory subunit ofCOX and mediates the higher level of energy production in targetcells by estrogen.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
Cytochrome c oxidase subunit 7A-related protein, mitochondrial, COX7a-related protein, Cytochrome c oxidase subunit VIIa-related protein, EB1, COX7A2L, COX7AR, COX7RP
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图像 |
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说明书 |
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数量 |
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